Why are proline and glycine helix breakers?
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Glycine, with no side chain, is a helix-breaker because rotation around both f and y is so unconstrained; recall the large area allowed to glycine on the Ramachandran diagram. Proline also is a helix-breaker because it has no backbone NH to hydrogen bond.
Glycine, with no side chain, is a helix-breaker because rotation around both f and y is so unconstrained; recall the large area allowed to glycine on the Ramachandran diagram. Proline also is a helix-breaker because it has no backbone NH to hydrogen bond.
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