Question

Why does volume overload on right heart produce pulmonary hypertension?

Answer 1

Answer:

Increased ventricular wall stress. The pulmonary vascular resistance (PVR) can increase up to 500%, causing pulmonary hypertension (PH). The resulting increase in RV wall stress is a key driver of RV changes in pressure overload. ... The RV remodels from a low-pressure to a high-pressure pump.