Question

Why the reaction of (ptcl4)2-with nh3 yields the cis product while the reaction of (pt (nh3)4)2+with cl-ion yields the trans product?

Answer 1

Explanation:

The reaction of (ptcl4)2-with nh3 yields the cis product while the reaction of (pt (nh3)4)2+with cl-ion yields the trans product.

Answer 2

The reaction of PtCl₄ with NH₃ yields cis product while Pt(NH₃)₄ reaction with chloride ion yields trans product because of the greater trans directing nature of chloride ion than ammonia.

• The trans effect of chloride ion is greater than ammonia. When an NH₃ group displaces a chloride ion in platinum chloride, the next incoming NH₃ orientation must be trans to chloride. Thus it turns out to be cis in orientation to NH₃, yielding cisplatin.
• In case of Pt(NH₃)₄ reaction with chloride ion, after one NH₃ group is replaced with chloride, the next incoming chloride will be directed to a trans position to the first chloride, yielding trans-platin.