Woukd you expect the partition coeffient to vary with temperature? Explain
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An inverse linear relationship was found between temperature and the partition coefficient. CONCLUSION: Within a specified range of temperatures, the partition coefficients isoflurane and sevoflurane decrease as the temperature increases. Sevoflurane shows a high solubility in Oxygent(TM) as compared to isoflurane.
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The solubility in the aqueous phase increases much more with temperature, as the solubility in the hydrophobic phase does.
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