Question

Write a note on Microbes in industrial vitamin production.

Answer 1

↵Vitamin B12 which forms an important part of the vitamin B complex is produced commercially on a large scale . It was  recovered  for the first time in active crystalline form from actinomycete Streptomyces griseus. Different methods are employed for its production and these are as follows:

Direct fermentation: In this method , Streptomyces griseus is grown on a culture medium under controlled conditions. Then Fermentation is carried out at 27˚C with aeration for about 5 days. The growth is harvested before mycelial autolysis and vitamin destruction. The vitamin is recovered from broth by filtration. .Bacillus megaterium, Propionibacterium freudenreichii, Propionibacterium shermanii and Pseudomonashas also been used for commercial production of vitamin B12

Indirect production: It is obtained as byproduct of antibiotic fermentation processes such as Streptomycin production

Genetic engineering: Genetic approaches like shuffling of genome have also been employed in Propionibacterium shermanii to improve yields of vitamin B12.

Answer 2

Dear Student,

● Microbes in industrial vitamin production -

• Vitamins are organic substances that are required in small quantities for normal growth and functions of body.
• Vitamins are not synthesized by humans but are supplied through diet.
• They are commercially produced by help of microorganisms.

# Microbes used for commercial production of various vitamins -

• Vitamin A - Blakeslea trispora, Phycomyces blakesleeanus
• Vitamin B2 - Clostridium aceto­butylicum, Clostridium butylicum
• Vitamin B12 - Streptomyces olivaceus, Cornybacterium species
• Vitamin C - Cornybactrium species
• Vitamin E - Euglena gracilis

Thanks dear. Hope this helps you..