write the different between apoenzyme and holoenzyme
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Enzymes are biocatalysts, which takes part in the chemical reactions of the body.
Explanation:
- Enzymes are proteins that catalyzes the biochemical reactions in the body. It is made up of sequence of animo acids which makes up proteins.
- Most enzymes require a small non protein part to initiate its function, these are called as called as Cofactors.
- These cofactors are generally made up of ions or other organic and inorganic molecules, and there is also a protein part which is binds with the enzymes and are necessary for their function, these protein part is called as Coenzyme.
- The binding of these cofactors is necessary for the enzyme to work effectively.
- When the coenzyme binds with the cofactor and the complete molecule is called as Holoenzyme.
- Holoenzyme is the active enzyme, DNA Polymerase and RNA Polymerase are the examples of Holoenzymes.
- Whereas Apoenzyme is the enzyme before the binding of the cofactor, and hence it is not active and doesn't take part in chemical reactions.
- Examples of Apoenzyme are NAD+, FAD, etc.
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