write the name of rate limiting enzyme of glycolysis?
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Regulation of the rate limiting enzymes. The four regulatory enzymes are hexokinase (or glucokinase in the liver), phosphofructokinase, and pyruvate kinase. The flux through the glycolytic pathway is adjusted in response to conditions both inside and outside the cell.
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Regulated only by excess glucose-6-phosphate. If G6P accumulates in the cell, there is feedback inhibition of hexokinase till the G6P is consumed. The phosphofructokinase step is rate-limiting step of glycolysis. High AMP/ADP levels are activators of this enzyme, while high ATP levels are inhibitory (energy charge).
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