Question

N. A nonsteroidal anti-inflammatory medication, c13h18o2, used especially in the treatment of arthritis and commonly taken for its analgesic and antipyretic properties

Answer 1

Ibuprofen

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LITERATURE

-Isobutylphenyl)propanoic acid; Motrin; Brufen; Advil   More...Molecular Formula:C13H18O2Molecular Weight:206.285 g/molInChI Key:HEFNNWSXXWATRW-UHFFFAOYSA-NSafety Summary:Laboratory Chemical Safety Summary (LCSS)Drug Information:Drug Indication  Therapeutic Uses  Clinical Trials  FDA Orange Book

Ibuprofen is a nonsteroidal anti-inflammatory agent with analgesic properties used in the treatment of RHEUMATISM and ARTHRITIS.

from MeSH

Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. (NCI05)

Pharmacology from NCIt

Ibuprofen is a commonly used nonsteroidal antiinflammatory (NSAID) drug which is available both by prescription and over-the-counter. Ibuprofen is considered to be among the safest NSAIDs and is generally well tolerated but can, nevertheless, rarely cause clinically apparent and serious acute liver injury.