Short note of allosteric inhibition
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✔️Allestoric inhibition :
Negative allosteric modulation (also known as allosteric inhibition) occurs when the binding of one ligand decreases the affinity for substrate at other active sites. For example, when 2,3-BPG binds to an allosteric site on hemoglobin, the affinity for oxygen of all subunits decreases.
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Here is your answer....
✔️Allestoric inhibition :
Negative allosteric modulation (also known as allosteric inhibition) occurs when the binding of one ligand decreases the affinity for substrate at other active sites. For example, when 2,3-BPG binds to an allosteric site on hemoglobin, the affinity for oxygen of all subunits decreases.
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Answer :-
First of all, what is Allosteric inhibition ?
Ans - "Allosteric inhibition" can be defined as the process of inhibition of enzymes which is caused by the product of an enzyme catalysed reaction.
Extra Information :-
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- Allosteric inhibition is also known as "Feedback inhibition".
- "Hexokinase" helps in the conversion of Glucose into Glucose-6-Phosphate.
- "Hexokinase" shows feedback inhibition.
- Glucose-6-Phosphate, the end product, can inhibit the activity of "Hexokinase".
- The phenomenon of the feedback inhibition of enzymes, is greatly influenced by the end product.
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