Question

what it kreb cycle? explain it​

Answer 1

Answer:

The Krebs cycle is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidization of acetate—derived from carbohydrates, fats, and proteins —into carbon dioxide. Theoretically there are several alternatives to the TCA cycle, but the TCA cycle appears to be the most efficient.

Answer 2

Answer:

KREB'S CYCLE

• The citric acid cycle, shown in —also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle—is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate—derived from carbohydrates, fats, and proteins—into carbon dioxide.

PURPOSE OF KREB CYCLE :-

• The citric acid cycle, also known as the Krebs cycle or the tricarboxylic acid cycle, is at the center of cellular metabolism, playing a starring role in both the process of energy production and biosynthesis. It finishes the sugar-breaking job started in glycolysis and fuels the production of ATP in the process.

STEPS OF KREB CYCLE :-

The TCA cycle is a central pathway that provides a unifying point for many metabolites, which feed in at various points. It takes place over eight different steps:

• The TCA cycle is a central pathway that provides a unifying point for many metabolites, which feed in at various points. It takes place over eight different steps:Step 1: Acetyl CoA (two carbon molecule) joins with oxaloacetate (4 carbon molecule) to form citrate (6 carbon molecule).

• Step 2: Citrate is converted to isocitrate (an isomer of citrate)

• Step 3: Isocitrate is oxidised to alpha-ketoglutarate (a five carbon molecule) which results in the release of carbon dioxide. One NADH molecule is formed.

☞NOTE :- The enzyme responsible for catalysing this step is isocitrate dehydrogenase. This is a rate limiting step as isocitrate dehydrogenase is an allosterically controlled enzyme.

• The enzyme responsible for catalysing this step is isocitrate dehydrogenase. This is a rate limiting step as isocitrate dehydrogenase is an allosterically controlled enzyme.

• Step 4: Alpha-ketoglutarate is oxidised to form a 4 carbon molecule. This binds to coenzyme A forming succinyl CoA. A second molecule of NADH is produced, alongside a second molecule of carbon dioxide

• Step 5: Succinyl CoA is then converted to succinate (4 carbon molecule) and one GTP molecule is produced.

• Step 6: Succinate is converted into fumarate (4 carbon molecule) and a molecule of FADH₂ is produced.

• Step 7: Fumarate is converted to malate (another 4 carbon molecule).

• Step 8: Malate is then converted into oxaloacetate. The third molecule of NADH is produced.

⛔ NONEXISTENT ⛔