Which one of the following amino acids is catalyzed by activated macrophages to produce
reactive nitrogen species?
(A) Arginine (B) Asparagine (C) Cysteine (D) Histidine
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(D) Histidine is a amino acids
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A. arginne.
Nitric oxide is produced from L-arginine by three main isoforms of nitric oxide synthase (NOS).
the efficient pathogen killing require colocalization of iNOS with pathogen containing compartments, the fact that NO can diffuse across cell membranes might allow for an antimicrobial activity at distance, even in those cases where NO acts in cells that do not express iNOS
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